529-1011-00L  Organic Chemistry I (for students of Biology, Pharmaceutical Sci., and Health Sci. & Tech.)

SemesterAutumn Semester 2020
LecturersC. Thilgen
Periodicityyearly recurring course
Language of instructionGerman


AbstractFundamentals of Organic Chemistry: molecular structure. Bonding and functional groups; nomenclature; resonance and aromaticity; stereochemistry; conformation; bond strength; organic acids and bases; basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.
ObjectiveUnderstanding the basic concepts and definitions of organic chemistry. Knowledge of the functional groups and classes of compounds that are important in biological systems. Foundations for the understanding of the relationship between structure and reactivity.
ContentOrganic molecules: Isolation, separation and characterization of organic compounds. Classical structure theory: constitution, covalent bonding, bonding geometry, functional groups, classes of compounds, nomenclature. Electron delocalization: resonance, aromaticity. Stereochemistry: chirality, configuration, topicity. Conformational analysis. Bond energies, non-covalent interactions. Organic acids and bases. Basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.
Lecture notesPrinted lecture notes are available. Exercises, answer keys and other handouts can be downloaded from the Moodle course "Organic Chemistry I" of the current semester (Link).
Literature• Basisbuch Organische Chemie. Carsten Schmuck, Pearson Studium, 2018. (Kompaktes Lehrbuch für die ersten beiden Semester; 412 S.).
• Organische Chemie. K. Peter C. Vollhardt, Neil E. Schore, Übers. hrsg. von Holger Butenschön, 5. Aufl., Wiley-VCH, 2011.
• Organic Chemistry: Structure and Function. K. Peter C. Vollhardt, Neil E. Schore, 7th ed., W. H. Freeman & Company, 2014.
• Organic Chemistry. T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder, 11th ed., internat. stud. vers., Wiley, Hoboken, N. J., 2014.
• Organische Chemie. J. Clayden, N. Greeves, S. Warren, 2. Aufl., Springer Spektrum, 2013.
• Organic Chemistry. J. Clayden, N. Greeves, S. Warren, 2nd ed., Oxford University Press, 2012.
• Organische Chemie. Paula Y. Bruice, 5. akt. Aufl., Pearson.
• Organic Chemistry (Global Edition). Paula Y. Bruice, 8th ed., Pearson.
• Essential Organic Chemistry (Global Edition). Paula Y. Bruice, 3rd ed., Pearson. (Designed for a one-term course)
• Organic Chemistry I as a Second Language – Translating the basic concepts (Taschenbuch mit Übungen: 656 Seiten). David R. Klein; Verlag: John Wiley & Sons Inc; ISBN-10: 0470198699, ISBN-13: 978-0470198698.
Prerequisites / NoticeThe course consists of lectures (36 hours) and problem-solving lessons (20 hours, groups of ca. 25 people). In addition, online exercises are available in the e-learning environment Moodle (Course OC I).